Month: March 2012

Compact microplate sealer handles all types and sizes

SEALING microplates is an important but routine laboratory task, usually done through the use of a microplate sealer. Many of these tools, however, are large and expensive, and require both electrical power and compressed air. Porvair Sciences’s new MiniSeal Plus…

Bromodomains and profiling kits to boost drug discovery

AMSBIO says that bromodomains – protein domains containing about 110 amino acid units – are emerging as a new class of target for drug discovery research, alongside Histone deacetylase (HDAC) and histone acetyltransferase (HAT). Bromodomains – BRDs – are found…

Sequencing the genome of antibiotic-resistant bacteria

A REPORT this week from Madrid recounts the novel use of the latest genomic sequencing system to unravel some of the secrets of new strains of the bacterium of Klebsiella pneunomiae. Researchers at the University Hospital La Paz Research Institute…

Next-generation mass spec made simpler

IN A BID to boost adoption of its next-generation mass spectrometry technology, AB Sciex has launched a bundled package of instruments plus software, training, standards, and validation services. The Accelerated Lab Integration Package is launched to coincide with the launch…

Transfection-free labelling for direct organelle visualisation

AN EASY method of labelling cellular structures without transfection agents is now available from Amsbio. The company says its lentiviral particles allow the direct visualisation of organelles and other internal cell structures, without manipulation. Real-time visualisation conventionally requires the use…

More efficient collagen coating of plates and flasks

A REGULAR but tedious task in many laboratories is the coating of disposable items of labware with extracellular matrix proteins such as collagen or fibronectin before performing cell culture operations. Now an application note from Integra Biosciences demonstrates how this…