Category: drug development

Compound library targets deubiquitylase enzymes

WHAT is claimed to be the first commercially available compound library of novel small molecules to target deubiquitylase (dub) enzymes has been launched by Ubiquigent. DUBtarget-001 has been developed with the University of Dundee, to support commercial and academic researchers…

Compound fragment library now ‘in the cloud’

Rainy day in Lanarkshire? Selcia compounds are now available through BioAscent's online rapid ordering system

OVER 1300 compounds from the Selcia compound fragment library are now available to researchers through the online Compound Cloud service of BioAscent Discovery. A new agreement between the companies means that Selcia’s 1366-fragment collection has been added to the 125,000…

FieldScreen screening software rebranded as Blaze

CRESSET has relaunched its FieldScreen system for ligand based virtual screening as Blazev10. This software uses the shape and electrostatic character of known ligands to search large chemical collections for molecules with similar properties, in order to return diverse new…

The latest trends in nucleotide innovation

LINK Technologies reports that it has observed a significant increase in requests for vitamin-modified oligo precursors, following on from the increasing use of vitamin-modified oligonucleotides in life science research. The company is a certified specialist in the provision of phosphoramidites…

Nanoscale thermal analysis to improve drug delivery

AT THE University of East Anglia, UK , post-doctoral researcher Jonathan Moffat is studying the delivery of drugs with poor water solubility, and looking in particular at the characterisation of delivery systems.   His team creates solid dispersions using a variety…

Planet xMap Europe registrations break 500 mark

THE TENTH annual Planet xMap symposium, to be held 10-11 October 2012 at the Grimaldi Forum in Monaco, has attracted over 500 delegate registrations reports Luminex. The symposium programme features scientific sessions, workshops, discussion groups, exhibitions, and networking events with…

Adme-Tox probes for multiplexed gene expression

PLEXPRESS says that researchers can now select from hundreds of genes and carry out reliable, accurate and cost-effective Adme-Tox (absorption, distribution, metabolism, and excretion toxicity) studies, thanks to its expanded library of pre-validated probes for multiplexed gene expression analysis. The…

Elisa kits measure anti-KLH antibodies

THE FIRST Elisa kit to exploit Stellar Biotechnologies’s Keyhole Limpet Hemocyanin (KLH) protiens is now available. This research-use-only (RUO) enzyme-linked immunosorbent assay (Elisa) is available in six different kits to kits to measure either immunoglobulin G (IgG) or immunoglobulin M…

Human mononuclear cells available off the shelf

SeraCare Life Sciences has expanded its range of mononuclear cells with the launch of off-the-shelf AccuCell human cord blood mononuclear cells (CBMNCs). Viability of these cells after thawing is validated at better than 90%, says SeraCare, making these cryopreserved CBMNCs…