Category: genomics

Top tips for gene silencing and delivery

A RAPIDLY growing area of genomics research is the field of gene silencing, particularly through the use of short interfering RNA (siRNA). This has become a useful tool for understanding the involvement of genes in disease states and pathways, and…

Stable phosphoramidites for oligonucleotide synthesis

TWO NEW new modified phosphoramidites have been launched to complement Link Technologies’s oligonucleotide synthesis support portfolio. Triplex, antisense, and gene targeting research may benefit from the company’s new RNA-type phosphoramidites, which it says provide nuclease resistance and stability. New ethyl…

How to go fishing in the deep end of the gene pool

AN APPLICATION note now available from Oxford Gene Technology provides scientists with valuable guidance on the use of targeted probes to improve data quality in next-generation sequencing. The note, titled Fishing for variants in the deep end of the gene…

Lab robots automate plant science at Danforth labs

A PRODUCTIVITY increase of 100 times, or 10,000 percent, is enough to make any laboratory manager sit up and pay attention. This is exactly what is being claimed for the installation of a customised Yeast 1 Hybrid automation system at…

Delivering RNAi agents into myeloid and neuronal cells

TWO NEW proprietary transduction reagents offer the directed delivery of RNAi agents into myeloid cells and neuronal cell, both primary and in cell lines. MyeloAim and NeuroAim, available from Bioo Scientific, can transduce siRNA to targeted cells for efficient gene…

Machine engineering at the genetic level

WE THINK of engineering as the creation of machines, while genetic engineering is the manipulation of genomes. These two disciplines come together in the International Genetically Engineered Machine (iGem) competition, which encourages students to exploit the growing power of biotechnology…

Assays promise a new approach to leukemia research

THE HIGH sensitivity detection of genetic variation in leukemia samples, made possible by the use of 454 sequencing via newly-released sequence-based assays, offers a new direction for cancer researchers says Roche. The company’s new GS GType Primer Sets allow the…

Data analysis package covers NGS, qPCR, and microarrays

INTEGROMICS says its new OmicsOffice platform is the first software bundle able to analyse data from NGS (next-generation sequencing), qPCR (quantitative polymerase chain reaction) and microarray experiments. OmicsOffice completes ‘Click And Go’ automatic workflows for RNAseq, ChipSeq, qPCR and microarray…

LGC opens new Boston lab

LGC Genomics has launched a new genomics services laboratory at the Cummings Centre near Boston, USA. The company, which merged with KBioscience in July 2011, has grown from just one to 20 US employees in the last year, so this…

Benchtop 454 sequencer gets software upgrade

A SOFTWARE upgrade for Roche’s 454 GS Junior benchtop next-generation genomic sequencing system promises better sequencing consistency. The 454 GS Junior is a benchtop version of the Genome Sequencer FLX, and says Roche has become well established in a number…