Researchers in Barcelona report progress in the use of 3D organoid technology to create an analogue of human colon cancer in a mouse model. The study, from the Institute for Research in Biomedicine (IRB), shows that the hormone (transforming growth…
STA Pharmaceutical and Regulus Therapeutics have entered into a collaboration agreement covering oligonucleotide synthesis for research and mid-scale non-GMP/cGMP manufacturing. STA becomes a strategic development and manufacturing partner for Regulus’s preclinical and clinical programmes of microRNA-targeting drugs. Regulus will provide…
WHAT is claimed to be the first commercially available compound library of novel small molecules to target deubiquitylase (dub) enzymes has been launched by Ubiquigent. DUBtarget-001 has been developed with the University of Dundee, to support commercial and academic researchers…
A FULLY-integrated technology platform designed to meet the needs of upstream bioprocessing laboratories has been launched by Sartorius Stedim Biotech. The Connect Upstream platform combines a high-performance expression system with equipment and process control systems, together promising to accelerate the…
OVER 1300 compounds from the Selcia compound fragment library are now available to researchers through the online Compound Cloud service of BioAscent Discovery. A new agreement between the companies means that Selcia’s 1366-fragment collection has been added to the 125,000…
CRESSET has relaunched its FieldScreen system for ligand based virtual screening as Blazev10. This software uses the shape and electrostatic character of known ligands to search large chemical collections for molecules with similar properties, in order to return diverse new…
LINK Technologies reports that it has observed a significant increase in requests for vitamin-modified oligo precursors, following on from the increasing use of vitamin-modified oligonucleotides in life science research. The company is a certified specialist in the provision of phosphoramidites…
AT THE University of East Anglia, UK , post-doctoral researcher Jonathan Moffat is studying the delivery of drugs with poor water solubility, and looking in particular at the characterisation of delivery systems. His team creates solid dispersions using a variety…
THE TENTH annual Planet xMap symposium, to be held 10-11 October 2012 at the Grimaldi Forum in Monaco, has attracted over 500 delegate registrations reports Luminex. The symposium programme features scientific sessions, workshops, discussion groups, exhibitions, and networking events with…
PLEXPRESS says that researchers can now select from hundreds of genes and carry out reliable, accurate and cost-effective Adme-Tox (absorption, distribution, metabolism, and excretion toxicity) studies, thanks to its expanded library of pre-validated probes for multiplexed gene expression analysis. The…