Analysing cell fermentation in high-throughput applications

ROCHE says its new Cedex Bio HT analyser gives highly reliable determination of metabolites and substrates in mammalian and microbial cell fermentation. The system delivers precise analytics, it says, to allow flexible adaption of additional test menus, and can process up to 120 tests per hour.

Designed for high-throughput applications such as in-process development, analyser data can be compared directly with data produced by Cedex Bio and Cedex Bio HT analysers anywhere in the world, making the instruments suited to high scale manufacturing in a global biotech production.

By minimising hands-on-time, the Cedex Bio HT promises greater precision, sensitivity, and linearity than instruments using membrane-based technology. It includes three different measuring methods enabling the analysis of IgG (immunoglobulin G) in addition to LDH (lactate dehydrogenase) and various substrates and metabolites as glutamate, glutamine, sodium, potassium, glucose, lactate, and ammonia.

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