THE ADOPTION of a custom UPLC heating block has improved productivity as well as producing more accurate and repeatable thermal stability measurements at a leading European contract research organisation (CRO), reports Asynt.
The organisation had previously used an offline source to heat samples coming from its UPLC system, but realised that the manual transfer of samples to and from the UPLC autosampler was a labour-intensive process.
Working with Asynt, it developed a new method using a custom-designed heating block to fit the UPLC autosampler, along with an offline heating tray compatible with a hotplate stirrer.
It has since found that the new method provides more uniform heating to the UPLC samples, eliminates sample mix-ups, and significantly reduce the labour demands of the process.