Category: crystallisation

A reactor at meso scale for when microfluidics would clog

MANY laboratory processes and reactions can be operated effectively at the micro scale, taking advantage of the growing usefulness of microfluidic technologies and micro-reactors. But many real-world operations involve suspended solids or other particles, which make micro-technologiess ineffective because the…

Micro bioreactor cultures insect cells at EMBL

TAP Biosystems reports that its Ambr micro bioreactor system is in use at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, for rapid small-scale parallel expression of human multi-protein complexes using baculovirus. The bioreactor is being used by scientists…

X-ray diffractometer optimised for structural biology

DESIGNED to meet the needs of the modern macromolecular crystallography laboratory, Agilent says its new GV1000 X-ray diffractometer is a revolutionary new instrument for the collection of high-quality diffraction data from crystalline samples of biological macromolecules. Launched this week at…

Crystallography studies boosted by pipetting innovation

AN AUTOMATED screen optimiser from TTP Labtech promises to deliver the simple, reliable and fast set-up of screen plates to streamline laboratory crystallography studies. The new instrument, called the Woodpecker, is to be unveiled next week at the American Crystallographic…

Protein crystallisation studies rely on temperature stage

TRADITIONAL methods for growing protein crystals are by microplate sitting-drop crystallisation, or hanging-drop methods based on vapour diffusion. These yield a limited number of crystals, but usually enough for biological research. At the Institute for Particle Science and Engineering at…

Plate reader includes on-board camera for well imaging

DESCRIBED as an evolution of its first dynamic light scattering (DLS) plate reader, Wyatt Technology’s new DynaPro Plate Reader II includes an onboard camera to take pictures of each microplate well. The new reader has an extended temperature range, from…

Putting the heat into crystallisation method development

A CUSTOM Asynt dry heating block is currently in use at the Wilson structural chemistry research group at the University of Bath, UK, is a project to simplify and accelerate crystallisation method development. The researchers are selectively controlling polymorph formation,…

Faster access to pure chiral compounds with screening kits

ORGANIC chemists can expect fast and easy access to optically-pure chiral compounds from their racemic mixtures when using the new Maybridge Chiral Resolution Screening and Purification Kits, says Thermo Fisher. Under normal circumstance, it can take days or even weeks…

A review of best crystallisation practice

A WHITE paper from Metler Toledo explores how process analytical technology (PAT) can improve batch purity, yield and repeatability in crystallisation and precipitation processes. Entitled New Technologies for Advanced Crystallization Development, the paper demonstrates how PAT offers improved accuracy, easier…