THE NEWEST addition to BMG Labtech’s range of microplate readers, the Nephelostar Plus, is said to be the world’s only laser-based nephelometer that measures light scattering in a microplate.
Nephelostar Plus from BMG Labtech
Light scattering is an alternative to absorbance studies, measuring the turbidity or solubility of a sample in solution.
The Nephelostar Plus microplate reader offers an easy to use, low cost, and rapid method for checking the solubility of compounds says BMG.
In addition, it offers microbiology laboratories a more precise method with a larger dynamic range to measure cellular growth.
The instrument detects insoluble particles in liquid samples by measuring forward scattered light. It has applications in compound solubility screening, microbial cell growth kinetics, antibody-antigen interaction, immunoprecipitation, and polymerisation monitoring.
The company claims that Nephelostar Plus can deliver up to 30 times the sensitivity of conventional readers that measure the absorbance via optical density.
Options to adjust the intensity and beam diameter of the laser light allow for more precise measurements in coloured or turbid solutions, and the adjustable beam diameter allows for measurements in 24, 48, 96 and 384-well microplate formats.
It is also said to be faster than using conventional solubility detection methods, providing a powerful alternative for compound solubility, microbial growth, or other light-scattering measurement applications.